Alcohol Linked to Higher Risk of Breast Cancer In African-American Women

That’s the finding in a just-published study in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

It’s not news that alcohol has been confirmed as a risk factor for breast cancer.  But all studies have limitations, and most of the studies that have been conducted involved white women.  Is it different if the woman is African-American?

In a word, No.

Melissa A. Troester, PhD, a professor of epidemiology and director of the Center for Environmental Health and Susceptibility in the Gillings School of Global Public Health at the University of North Carolina and colleagues enrolled 22,338 women from the African American Breast Cancer Epidemiology and Risk (AMBER) Consortium, which encompasses four large epidemiologic studies of breast cancer.

Study participants reported their alcohol intake via a questionnaire, and researchers used logistic regression to estimate the association between alcohol consumption and cases of breast cancer.

The study showed that women who drank seven or more drinks per week showed an increased risk of almost all subtypes. Women who drank 14 or more alcoholic beverages per week were 33 percent more likely to develop breast cancer than women who consumed four or fewer drinks per week.

Overall, Troester said, black women drink less alcohol than white women, with previous research suggesting a range of reasons from religious restrictions to health restrictions. In this study, 45 percent of the women were “never drinkers,” and researchers found that the “never drinkers” were more likely to develop breast cancer than the light drinkers.

Troester said that they did not identify the causes for increased risk in never drinkers, but previous studies finding similar elevated risk in never drinkers implicate the comorbidities, such as diabetes, that influenced them to avoid alcohol.

“Alcohol is an important modifiable exposure, whereas many other risk factors are not,” she said. “Women who are concerned about their risk of breast cancer could consider reducing levels of exposure.”

Troester said that further research would be necessary to determine which breast cancer risk factors–weight, reproductive history, oral contraceptive use, family history, etc.–apply most significantly to each race. “Understanding the impact of these various risk factors could help narrow the disparity in breast cancer incidence and mortality,” she said.

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